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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1987-6-17
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pubmed:abstractText |
Limited information is available regarding the incidence, nature, and treatment of behavioral problems in Alzheimer's disease (AD). A chart review of 57 outpatients with a diagnosis of AD was conducted to examine these issues. Thirty-three (58%) patients had significant behavioral symptomatology (most commonly delusions, nonspecific agitation, and diurnal rhythm disturbances). Twenty-seven were treated with thioridazine (10-250 mg/day), 15 (55.6%) of whom were judged to have a positive response (mean maximum dose = 55 mg/day). Information regarding the characteristic phenomenology of the behavioral symptoms studied was used to design a clinical rating instrument for AD patients, the Behavioral Pathology in Alzheimer's Disease Rating Scale (BEHAVE-AD), which should be useful in prospective studies of behavioral symptoms as well as in pharmacologic trials.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0160-6689
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48 Suppl
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
9-15
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3553166-Aged,
pubmed-meshheading:3553166-Alzheimer Disease,
pubmed-meshheading:3553166-Circadian Rhythm,
pubmed-meshheading:3553166-Clinical Trials as Topic,
pubmed-meshheading:3553166-Delusions,
pubmed-meshheading:3553166-Female,
pubmed-meshheading:3553166-Humans,
pubmed-meshheading:3553166-Male,
pubmed-meshheading:3553166-Middle Aged,
pubmed-meshheading:3553166-Prospective Studies,
pubmed-meshheading:3553166-Psychiatric Status Rating Scales,
pubmed-meshheading:3553166-Psychometrics,
pubmed-meshheading:3553166-Psychomotor Agitation,
pubmed-meshheading:3553166-Thioridazine
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pubmed:year |
1987
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pubmed:articleTitle |
Behavioral symptoms in Alzheimer's disease: phenomenology and treatment.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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