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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1987-5-4
|
| pubmed:abstractText |
Following digestion of a single pancreas from 30- to 50-day-old Sprague Dawley rats, many single cells and small cell clusters were obtained. Over a succeeding 5-day interval in tissue culture, many islet-like cell clusters were noted. They were smaller than isolated intact rat islets and appeared to develop from selective aggregation of islet cells. More than 1,000 of these islet-like clusters were obtained from a single pancreas. The physiologic characteristics of these cells indicated preservation of insulin secretory responses to glucose (30, 50, 100, 150, 200, and 300 mg/dl), theophylline (1.5 mM), and arginine (10 mM). This appears to be a useful method to follow when large quantities of islet cells are required, as for transplantation.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0885-3177
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
1
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
494-7
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading | |
| pubmed:year |
1986
|
| pubmed:articleTitle |
A culture method for the isolation of pancreatic islet cells from young rats.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|