Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1978-10-27
|
pubmed:abstractText |
A double-blind 4-week trial of cimetidine (1 g daily) versus placebo was conducted in 68 adult outpatients with active duodenal ulceration endoscopically confirmed. 3 of the patient admitted to the study (1 on cimetidine and 2 on placebo) did not complete the trial. After 4 weeks of treatment, 25 of 33 patients (76%) receiving cimetidine had healed their ulcers compared with 15 (47%) of 32 patients receiving placebo (p less than 0.02). Antacid consumption was also significantly decreased by cimetidine when compared with placebo. Tolerability of the drug was good.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0012-2823
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
17
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
383-6
|
pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:355027-Administration, Oral,
pubmed-meshheading:355027-Adult,
pubmed-meshheading:355027-Cimetidine,
pubmed-meshheading:355027-Clinical Trials as Topic,
pubmed-meshheading:355027-Double-Blind Method,
pubmed-meshheading:355027-Drug Evaluation,
pubmed-meshheading:355027-Duodenal Ulcer,
pubmed-meshheading:355027-Endoscopy,
pubmed-meshheading:355027-Female,
pubmed-meshheading:355027-Guanidines,
pubmed-meshheading:355027-Humans,
pubmed-meshheading:355027-Male,
pubmed-meshheading:355027-Placebos
|
pubmed:year |
1978
|
pubmed:articleTitle |
Treatment of active duodenal ulcer with oral cimetidine: a multicenter controlled endoscopic trial.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial
|