| pubmed-article:3546627 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3546627 | lifeskim:mentions | umls-concept:C0013254 | lld:lifeskim |
| pubmed-article:3546627 | lifeskim:mentions | umls-concept:C0303611 | lld:lifeskim |
| pubmed-article:3546627 | lifeskim:mentions | umls-concept:C0678609 | lld:lifeskim |
| pubmed-article:3546627 | lifeskim:mentions | umls-concept:C1659427 | lld:lifeskim |
| pubmed-article:3546627 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:3546627 | pubmed:dateCreated | 1987-4-3 | lld:pubmed |
| pubmed-article:3546627 | pubmed:abstractText | Aerosols of 99mTc diethylenetriaminepentaacetic acid ([99mTc]DTPA) used for measuring lung permeability and lung ventilation require a radioaerosol delivery system to produce an aerosol with reproducible size and radiochemical purity. To test how well nebulizers meet this requirement, radiochemical purity of aerosols produced with a jet and an ultrasonic nebulizer was evaluated. The activity median aerodynamic diameter (AMAD) and geometric standard deviation (sigma g) of radioaerosols were 0.46 micron (sigma g = 1.6) for the jet nebulizer and 0.70 micron (sigma g = 1.7) for the ultrasonic nebulizer. Paper and liquid chromatographic assays were obtained on the [99mTc]DTPA aerosol solute produced with each nebulizer. The results of these tests showed major differences in radiochemical purity. Aerosols produced in the jet nebulizer consistently showed greater than 90% of the radioactivity bound to the DTPA ligand whereas aerosols produced in the ultrasonic nebulizer showed less than 10% of the radioactivity bound to DTPA. The results support the need to test radiochemical purity of aerosols before using an aerosol nebulizer for pulmonary imaging and clearance studies. | lld:pubmed |
| pubmed-article:3546627 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3546627 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3546627 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3546627 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3546627 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3546627 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3546627 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3546627 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3546627 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:3546627 | pubmed:issn | 0161-5505 | lld:pubmed |
| pubmed-article:3546627 | pubmed:author | pubmed-author:WeberD ADA | lld:pubmed |
| pubmed-article:3546627 | pubmed:author | pubmed-author:HydeR WRW | lld:pubmed |
| pubmed-article:3546627 | pubmed:author | pubmed-author:UtellM JMJ | lld:pubmed |
| pubmed-article:3546627 | pubmed:author | pubmed-author:MorrowP EPE | lld:pubmed |
| pubmed-article:3546627 | pubmed:author | pubmed-author:OberdörsterGG | lld:pubmed |
| pubmed-article:3546627 | pubmed:author | pubmed-author:WaldmanD LDL | lld:pubmed |
| pubmed-article:3546627 | pubmed:author | pubmed-author:DragoS RSR | lld:pubmed |
| pubmed-article:3546627 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3546627 | pubmed:volume | 28 | lld:pubmed |
| pubmed-article:3546627 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3546627 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3546627 | pubmed:pagination | 378-82 | lld:pubmed |
| pubmed-article:3546627 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:3546627 | pubmed:meshHeading | pubmed-meshheading:3546627-... | lld:pubmed |
| pubmed-article:3546627 | pubmed:meshHeading | pubmed-meshheading:3546627-... | lld:pubmed |
| pubmed-article:3546627 | pubmed:meshHeading | pubmed-meshheading:3546627-... | lld:pubmed |
| pubmed-article:3546627 | pubmed:meshHeading | pubmed-meshheading:3546627-... | lld:pubmed |
| pubmed-article:3546627 | pubmed:meshHeading | pubmed-meshheading:3546627-... | lld:pubmed |
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| pubmed-article:3546627 | pubmed:meshHeading | pubmed-meshheading:3546627-... | lld:pubmed |
| pubmed-article:3546627 | pubmed:meshHeading | pubmed-meshheading:3546627-... | lld:pubmed |
| pubmed-article:3546627 | pubmed:meshHeading | pubmed-meshheading:3546627-... | lld:pubmed |
| pubmed-article:3546627 | pubmed:meshHeading | pubmed-meshheading:3546627-... | lld:pubmed |
| pubmed-article:3546627 | pubmed:meshHeading | pubmed-meshheading:3546627-... | lld:pubmed |
| pubmed-article:3546627 | pubmed:meshHeading | pubmed-meshheading:3546627-... | lld:pubmed |
| pubmed-article:3546627 | pubmed:meshHeading | pubmed-meshheading:3546627-... | lld:pubmed |
| pubmed-article:3546627 | pubmed:meshHeading | pubmed-meshheading:3546627-... | lld:pubmed |
| pubmed-article:3546627 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3546627 | pubmed:articleTitle | Chemical breakdown of technetium-99m DTPA during nebulization. | lld:pubmed |
| pubmed-article:3546627 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3546627 | pubmed:publicationType | Comparative Study | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3546627 | lld:pubmed |
