Linked Life Data

3539866

Source:http://linkedlifedata.com/resource/pubmed/id/3539866

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1987-2-19
pubmed:abstractText
The prevalence of seropositivity to Legionella spp. was studied in 184 children with bronchial asthma and in 80 control children, age- and sex-matched, without respiratory tract infections. The sera were examined by indirect immunofluorescence with antigens of six Legionella spp. The asthmatic children showed a significantly higher percentage of seroreactions to L. pneumophila than did the control children. In the asthmatic children, no association was found between age, sex, onset of asthmatic symptoms, living conditions, corticosteroid treatment, or exposure to aerosols and seropositivity to Legionella. No correlation could be found between the asthma severity score and the titer of serum antibodies to L. pneumophila. None of the 32 sera with titers of 256 or higher were reactive for Legionella-specific IgE antibodies. L. pneumophila antigen was detected in the urine of three children by an enzyme-linked immunosorbent assay (ELISA). The high prevalence of antibodies to L. pneumophila found in children with bronchial asthma, together with the detection of antigen in the urine of some of them, suggest that this group of children are highly susceptible to Legionnaires' Disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0021-2180
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
733-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Predisposition of the asthmatic child to legionellosis?
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't