Linked Life Data

3539662

Source:http://linkedlifedata.com/resource/pubmed/id/3539662

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1987-1-27
pubmed:abstractText
We have produced a monoclonal antibody, designated SN1, which binds to the surfaces of a subpopulation of avian sensory neurons, but not to other neurons of the peripheral or central nervous systems. The proportion of SN1(+) neurons in brachial and lumbosacral dorsal root ganglia (DRG), which innervate the wings and legs respectively, is low (30-40%), compared to the proportion (80-90%) in the lower thoracic DRG. SN1 immunoreactive fibers project to laminae I and II of the spinal cord dorsal horn, and are seen in the skin, but not the deeper tissues of older embryos. On the basis of the time of appearance, axial level-dependent distribution, and the central and peripheral projections of SN1(+) neurons, we suggest that they are cutaneous afferents that depend on interaction with peripheral targets to differentiate.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0012-1606
pubmed:author
pubmed:issnType
Print
pubmed:volume
118
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
494-504
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
A monoclonal antibody (SN1) identifies a subpopulation of avian sensory neurons whose distribution is correlated with axial level.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.