Linked Life Data

3534865

Source:http://linkedlifedata.com/resource/pubmed/id/3534865

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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1986-12-5
pubmed:abstractText
The aim of this study was to evaluate the effect of captopril on carbohydrate metabolism in diabetic patients with essential arterial hypertension. Sixteen patients with non-insulin-dependent diabetes mellitus and hypertension were studied. Captopril was employed in different doses, and where patients receiving 100 mg/day remained hypertensive, hydrochlorothiazide 50 mg/day was added. Treatment was maintained for 90 days in 14 patients, 2 being excluded because of side effects. Basal blood pressure was normalized in 8 patients (57%) with captopril alone, and in 6 patients (43%) following the addition of hydrochlorothiazide. Basal glucose levels were not altered. Oral glucose tolerance tests performed during captopril treatment showed a lower glucose response, without changes in the insulin response. There was significant weight loss during the study. We conclude that captopril appears to be a safe treatment in essential hypertension associated with non-insulin-dependent diabetes mellitus, producing no deleterious effects on metabolic control.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0032-5473
pubmed:author
pubmed:issnType
Print
pubmed:volume
62 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
66-8
pubmed:dateRevised
2009-10-22
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Effect of converting enzyme inhibitors in hypertensive patients with non-insulin-dependent diabetes mellitus.
pubmed:publicationType
Journal Article