pubmed-article:3533975 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3533975 | lifeskim:mentions | umls-concept:C0006836 | lld:lifeskim |
pubmed-article:3533975 | lifeskim:mentions | umls-concept:C0006837 | lld:lifeskim |
pubmed-article:3533975 | lifeskim:mentions | umls-concept:C0002351 | lld:lifeskim |
pubmed-article:3533975 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
pubmed-article:3533975 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:3533975 | pubmed:dateCreated | 1986-12-2 | lld:pubmed |
pubmed-article:3533975 | pubmed:abstractText | Eighty-three serum specimens from 24 patients infected with Candida albicans were examined for circulating Candida protein antigens with the Candida Detection System (CAND-TEC; Ramco Laboratories, Inc., Houston, Tex.). The medical records of each patient were reviewed for clinical evidence of Candida colonization or disease, predisposing factors for infection, underlying illness, the presence of a contaminated indwelling venous catheter, intravenous amphotericin B therapy, and outcome. Forty-nine serum specimens with antigen titers of 1:2 or less were obtained either from colonized patients or at a time when disseminated disease was not yet clinically suspected. Except for five specimens from two colonized patients, one with a contaminated arterial line, the other specimens with titers of 1:8 or greater (n = 14) were obtained from patients who had been clinically diagnosed and treated for disseminated candidiasis. Serum specimens with titers of 1:4 were often from patients with deep-seated candidal infection but were not uniformly diagnostic; in this situation additional specimens should be tested for Candida antigen titers. Only 1 of 24 serum specimens from patients with no evidence of C. albicans infection had a Candida protein antigen titer of 1:8. With a 1:8 or greater titer as a criterion for dissemination, the sensitivity of the CAND-TEC system was 71%, with a specificity of 98%. If the 1:8 titer for the colonized patient with a contaminated arterial line is not considered a false-positive result, the CAND-TEC sensitivity was 83%. The latex agglutination assay appears to be a useful, rapid, and noninvasive means of laboratory diagnosis of systemic candidiasis. The recovery of C. albicans from at least three body sites may also be a useful predictor of disseminated disease. | lld:pubmed |
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pubmed-article:3533975 | pubmed:language | eng | lld:pubmed |
pubmed-article:3533975 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3533975 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:3533975 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3533975 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3533975 | pubmed:month | Oct | lld:pubmed |
pubmed-article:3533975 | pubmed:issn | 0095-1137 | lld:pubmed |
pubmed-article:3533975 | pubmed:author | pubmed-author:TiltonR CRC | lld:pubmed |
pubmed-article:3533975 | pubmed:author | pubmed-author:DontaS TST | lld:pubmed |
pubmed-article:3533975 | pubmed:author | pubmed-author:FungJ CJC | lld:pubmed |
pubmed-article:3533975 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3533975 | pubmed:volume | 24 | lld:pubmed |
pubmed-article:3533975 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3533975 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3533975 | pubmed:pagination | 542-7 | lld:pubmed |
pubmed-article:3533975 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
pubmed-article:3533975 | pubmed:meshHeading | pubmed-meshheading:3533975-... | lld:pubmed |
pubmed-article:3533975 | pubmed:meshHeading | pubmed-meshheading:3533975-... | lld:pubmed |
pubmed-article:3533975 | pubmed:meshHeading | pubmed-meshheading:3533975-... | lld:pubmed |
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pubmed-article:3533975 | pubmed:meshHeading | pubmed-meshheading:3533975-... | lld:pubmed |
pubmed-article:3533975 | pubmed:year | 1986 | lld:pubmed |
pubmed-article:3533975 | pubmed:articleTitle | Candida detection system (CAND-TEC) to differentiate between Candida albicans colonization and disease. | lld:pubmed |
pubmed-article:3533975 | pubmed:publicationType | Journal Article | lld:pubmed |
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