Linked Life Data

3533299

Source:http://linkedlifedata.com/resource/pubmed/id/3533299

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1986-11-24
pubmed:abstractText
Studies coordinated by the World Health Organization were conducted in seven clinical centres on the chemotherapy of human echinococcosis with mebendazole, albendazole, and flubendazole. The first phase of these ended with the following conclusions.Treatment of 85 patients with mebendazole for cystic (Echinococcus granulosus) echinococcosis was successful in 8 patients and partially successful in 4 others. Flubendazole was effective in only one case of lung echinococcosis. Albendazole was successful in 5 of 30 patients treated and partially successful in 4 others. Further studies on new drugs or new formulations of existing benzimidazoles and on better forms of their application are needed. In the mean time, chemotherapy of human cystic echinococcosis should be restricted to inoperable cases.In 54 patients with E. multilocularis echinococcosis, it was confirmed that mebendazole therapy may arrest the development of the lesions. This treatment is therefore indicated in most cases of alveolar echinococcosis with or without surgery. However, further studies are needed to clarify the optimal regimen for mebendazole treatment and to explore the effectiveness of albendazole therapy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0042-9686
pubmed:author
pubmed:issnType
Print
pubmed:volume
64
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
383-8
pubmed:dateRevised
2010-10-26
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Multicentre clinical trials of benzimidazolecarbamates in human echinococcosis.
pubmed:publicationType
Journal Article, Clinical Trial