Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
37
pubmed:dateCreated
1986-11-19
pubmed:abstractText
52 asthmatic patients aged 18 to 70 years took part in a double-blind crossover trial comparing the effects of regular treatment of asthma with inhaled salbutamol (400 micrograms qds) versus irregular treatment (400 micrograms prn), each prescribed for 4 weeks. There were no differences between the two schedules regarding intensity of clinical symptoms, morning and evening values of peak expiratory flow rates and spirometric measurements. The mean daily consumption of salbutamol was higher in the period of regular treatment (2148 +/- 548 micrograms) than in the period of free treatment (800 +/- 700 micrograms). Patients expressed an obvious preference for the period of regular treatment (26 vs 13). Salbutamol given prn or on a regular qds regimen was shown to be equally effective and safe in controlling the signs and symptoms of asthma. No tolerance or drug abuse was observed. In view of the patients' preference for regular treatment, this schedule is a safe alternative in cases where low-dose symptomatic treatment given prn fails to alleviate symptoms.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0036-7672
pubmed:author
pubmed:issnType
Print
pubmed:day
13
pubmed:volume
116
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1260-3
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
[Comparative study of the effects of regular or on-demand salbutamol inhalation in the treatment of asthma].
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, English Abstract, Randomized Controlled Trial, Controlled Clinical Trial