| pubmed-article:3529082 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3529082 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:3529082 | lifeskim:mentions | umls-concept:C1519249 | lld:lifeskim |
| pubmed-article:3529082 | pubmed:issue | 17 | lld:pubmed |
| pubmed-article:3529082 | pubmed:dateCreated | 1986-10-3 | lld:pubmed |
| pubmed-article:3529082 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3529082 | pubmed:abstractText | A human fetal liver cDNA library was screened at reduced hybridization stringency for v-raf-related sequences. In addition to the expected c-raf-1 cDNA, a second sequence was isolated. Comparison of the second gene (pks) to the other raf-related sequences revealed nucleotide homologies of 71%. The predicted amino acid sequence of the kinase domain is sufficiently similar to that of v-raf to suggest that pks may encode a polypeptide that exhibits serine/threonine kinase activity. The expression of pks mRNA (2.7 kilobases long) is elevated in peripheral blood mononuclear cells isolated from two patients with angioimmunoblastic lymphadenopathy with dysproteinemia, a disease in which autoantibodies are produced following the lymphoproliferative activation of B cells. Analysis of somatic cell hybrids for segregation of the pks locus revealed the presence of an additional locus closely related to the pks sequence. | lld:pubmed |
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| pubmed-article:3529082 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3529082 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3529082 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:3529082 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3529082 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:3529082 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:3529082 | pubmed:author | pubmed-author:ShowsT BTB | lld:pubmed |
| pubmed-article:3529082 | pubmed:author | pubmed-author:MarkG EGE | lld:pubmed |
| pubmed-article:3529082 | pubmed:author | pubmed-author:MountzJ DJD | lld:pubmed |
| pubmed-article:3529082 | pubmed:author | pubmed-author:SeeleyT WTW | lld:pubmed |
| pubmed-article:3529082 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3529082 | pubmed:volume | 83 | lld:pubmed |
| pubmed-article:3529082 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3529082 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3529082 | pubmed:pagination | 6312-6 | lld:pubmed |
| pubmed-article:3529082 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:3529082 | pubmed:meshHeading | pubmed-meshheading:3529082-... | lld:pubmed |
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| pubmed-article:3529082 | pubmed:meshHeading | pubmed-meshheading:3529082-... | lld:pubmed |
| pubmed-article:3529082 | pubmed:meshHeading | pubmed-meshheading:3529082-... | lld:pubmed |
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| pubmed-article:3529082 | pubmed:meshHeading | pubmed-meshheading:3529082-... | lld:pubmed |
| pubmed-article:3529082 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:3529082 | pubmed:articleTitle | Pks, a raf-related sequence in humans. | lld:pubmed |
| pubmed-article:3529082 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3529082 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3529082 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:369 | entrezgene:pubmed | pubmed-article:3529082 | lld:entrezgene |
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