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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1986-9-17
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pubmed:abstractText |
We evaluated the natural course of delta superinfection in patients with chronic B viral hepatitis by examining serial liver biopsy specimens from 23 patients. The mean follow-up period was 2.5 years, and the average number of liver biopsies per patient was 2.8. The striking features were: (i) the prolonged acute hepatitis-like necroinflammatory activity (mean = 15 months) following acute delta hepatitis and (ii) rapid progression to severe forms of liver disease within a mean interval of 24 months from the onset of delta superinfection. Although there was a high frequency of stainable delta antigen (90%) in these liver biopsy specimens, there was no correlation between the degree of positivity and the histopathological changes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0270-9139
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
640-4
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pubmed:dateRevised |
2006-4-13
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pubmed:meshHeading |
pubmed-meshheading:3525368-Antibodies, Viral,
pubmed-meshheading:3525368-Biopsy,
pubmed-meshheading:3525368-Follow-Up Studies,
pubmed-meshheading:3525368-Hepatitis B,
pubmed-meshheading:3525368-Hepatitis B Surface Antigens,
pubmed-meshheading:3525368-Hepatitis B virus,
pubmed-meshheading:3525368-Hepatitis D,
pubmed-meshheading:3525368-Hepatitis Delta Virus,
pubmed-meshheading:3525368-Histocytochemistry,
pubmed-meshheading:3525368-Humans,
pubmed-meshheading:3525368-Immunoenzyme Techniques,
pubmed-meshheading:3525368-Immunoglobulin G,
pubmed-meshheading:3525368-Immunoglobulin M,
pubmed-meshheading:3525368-Liver,
pubmed-meshheading:3525368-Liver Cirrhosis,
pubmed-meshheading:3525368-Radioimmunoassay
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pubmed:articleTitle |
Natural course of delta superinfection in chronic hepatitis B virus-infected patients: histopathologic study with multiple liver biopsies.
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pubmed:publicationType |
Journal Article
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