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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1986-8-7
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pubmed:abstractText |
Cinoxacin (CINX) was administered twice a day for 7 consecutive days (400 mg X 2/day) to 34 female patients suffering from acute simple cystitis. The overall clinical efficacy was excellent in 15 cases (94%) and moderate in one case (6%) according to the criteria for clinical evaluation by the UTI committee. The efficacy was not determined in 18 cases. Bacteriological examination revealed 11 cases of single infection by E. coli, 2 cases of single infection by P. cepacia and S. epidermidis and one case of single infection by S. sunguis. MIC of E. coli ranged from 3.13 to 6.25 micrograms/ml. MIC of P. cepacia was 3.13 micrograms/ml and MIC of S. epidermidis more than 100 micrograms/ml. All the strains were eradicated with the efficacy of 100%. There was no relapse of acute simple cystitis in 16 cases after 7 days treatment of CINX. No serious side effects were recognized except for slight general fatigue and heart burn in 2 cases. It was thus concluded that CINX is clinically effective and safe for acute simple cystitis caused by E. coli and P. cepacia.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0018-1994
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
293-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3524157-Acute Disease,
pubmed-meshheading:3524157-Adolescent,
pubmed-meshheading:3524157-Adult,
pubmed-meshheading:3524157-Aged,
pubmed-meshheading:3524157-Cinoxacin,
pubmed-meshheading:3524157-Cystitis,
pubmed-meshheading:3524157-Drug Evaluation,
pubmed-meshheading:3524157-Drug Resistance, Microbial,
pubmed-meshheading:3524157-Escherichia coli,
pubmed-meshheading:3524157-Female,
pubmed-meshheading:3524157-Humans,
pubmed-meshheading:3524157-Middle Aged,
pubmed-meshheading:3524157-Pseudomonas,
pubmed-meshheading:3524157-Pyridazines
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pubmed:year |
1986
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pubmed:articleTitle |
[Clinical study of cinoxacin in acute simple cystitis].
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pubmed:publicationType |
Journal Article,
English Abstract
|