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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1986-6-27
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pubmed:abstractText |
Three experiments were conducted in which an illness-inducing immunosuppressant, cyclophosphamide (an unconditioned stimulus, US) was associated with a previously presented saccharin solution conditioned stimulus (CS). In each experiment, reexposure to the CS produced a conditioned suppression of the plaque-forming-cell response in the experimental groups. Experiment I demonstrated this result with Fisher 344 rats. Experiment II replicated the effect with Balb/c mice. In Experiment III conditioned immunosuppression was demonstrated when mice received CS-US delays as long as 6 hours. No evidence of a delay gradient was present in either the behavioral or the immunologic data. These parallel findings offer no support for the idea of a dissociation between the taste aversion and conditioned immunosuppression processes.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0031-9384
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
731-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3520612-Analysis of Variance,
pubmed-meshheading:3520612-Animals,
pubmed-meshheading:3520612-Cyclophosphamide,
pubmed-meshheading:3520612-Drinking Behavior,
pubmed-meshheading:3520612-Female,
pubmed-meshheading:3520612-Hemolytic Plaque Technique,
pubmed-meshheading:3520612-Immunosuppression,
pubmed-meshheading:3520612-Mice,
pubmed-meshheading:3520612-Mice, Inbred BALB C,
pubmed-meshheading:3520612-Rats,
pubmed-meshheading:3520612-Rats, Inbred F344,
pubmed-meshheading:3520612-Saccharin,
pubmed-meshheading:3520612-Species Specificity
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pubmed:year |
1986
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pubmed:articleTitle |
Some parameters of conditioned immunosuppression: species difference and CS-US delay.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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