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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1986-7-18
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pubmed:abstractText |
Concentrations of the alpha-, beta-, and gamma-subunits of enolase in surgically resected tumors and serum obtained from patients with various endocrine tumors were measured by a sensitive enzyme immunoassay system. Tissue concentrations of the gamma-subunit were significantly elevated in patients with neuroendocrine tumors concurrent with high concentrations of the gamma-subunit in their serum, which fell to normal in 90% of those who underwent tumor resection. Immunohistochemical analysis revealed that considerable amounts of the gamma-subunit were contained specifically in these tumors. These results indicate that the gamma-subunit of enolase is a useful marker for diagnosing and monitoring patients with neuroendocrine tumors.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0021-972X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
94-101
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3519652-Adult,
pubmed-meshheading:3519652-Calcitonin,
pubmed-meshheading:3519652-Carcinoembryonic Antigen,
pubmed-meshheading:3519652-Carcinoma,
pubmed-meshheading:3519652-Endocrine System Diseases,
pubmed-meshheading:3519652-Histocytochemistry,
pubmed-meshheading:3519652-Humans,
pubmed-meshheading:3519652-Immunoenzyme Techniques,
pubmed-meshheading:3519652-Male,
pubmed-meshheading:3519652-Neoplasms,
pubmed-meshheading:3519652-Peptide Fragments,
pubmed-meshheading:3519652-Phosphopyruvate Hydratase,
pubmed-meshheading:3519652-Thyroid Neoplasms
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pubmed:year |
1986
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pubmed:articleTitle |
Enolase subunits in patients with neuroendocrine tumors.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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