| pubmed-article:3516471 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3516471 | lifeskim:mentions | umls-concept:C0024432 | lld:lifeskim |
| pubmed-article:3516471 | lifeskim:mentions | umls-concept:C1171362 | lld:lifeskim |
| pubmed-article:3516471 | lifeskim:mentions | umls-concept:C0085355 | lld:lifeskim |
| pubmed-article:3516471 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:3516471 | lifeskim:mentions | umls-concept:C1515670 | lld:lifeskim |
| pubmed-article:3516471 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:3516471 | pubmed:dateCreated | 1986-6-18 | lld:pubmed |
| pubmed-article:3516471 | pubmed:abstractText | Leu-M2 (Mac-120) is a mouse anti-human monoclonal antibody that reacts with an antigen on the surface of most peripheral blood monocytes. The presence of Leu-M2 positivity has been associated with the capacity of monocytes to present antigen to T cells. We found that anti-Leu-M2 does not react with an intrinsic monocyte antigen but instead binds to platelets present on the surface of monocytes. Leu-M2 staining is lost from monocytes after they are treated with calcium chelating agents which remove platelets bound to the monocyte surface. Staining for Leu-M2 can be reintroduced by incubating monocytes with autologous platelets. Human alveolar, peritoneal, and tissue macrophages and the U937 cell failed to stain for Leu-M2 antigen. Leu-M2 does not appear to represent either platelet glycoprotein IIb/IIIa or thrombospondin. Our study underscores the importance of carefully screening antimonocyte antibodies for their reactivity with platelets. | lld:pubmed |
| pubmed-article:3516471 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3516471 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3516471 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3516471 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3516471 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3516471 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3516471 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3516471 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3516471 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3516471 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:3516471 | pubmed:issn | 0090-1229 | lld:pubmed |
| pubmed-article:3516471 | pubmed:author | pubmed-author:ColvinR BRB | lld:pubmed |
| pubmed-article:3516471 | pubmed:author | pubmed-author:KurnickJ TJT | lld:pubmed |
| pubmed-article:3516471 | pubmed:author | pubmed-author:AmentoE PEP | lld:pubmed |
| pubmed-article:3516471 | pubmed:author | pubmed-author:KradinR LRL | lld:pubmed |
| pubmed-article:3516471 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3516471 | pubmed:volume | 39 | lld:pubmed |
| pubmed-article:3516471 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3516471 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3516471 | pubmed:pagination | 442-51 | lld:pubmed |
| pubmed-article:3516471 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:3516471 | pubmed:meshHeading | pubmed-meshheading:3516471-... | lld:pubmed |
| pubmed-article:3516471 | pubmed:meshHeading | pubmed-meshheading:3516471-... | lld:pubmed |
| pubmed-article:3516471 | pubmed:meshHeading | pubmed-meshheading:3516471-... | lld:pubmed |
| pubmed-article:3516471 | pubmed:meshHeading | pubmed-meshheading:3516471-... | lld:pubmed |
| pubmed-article:3516471 | pubmed:meshHeading | pubmed-meshheading:3516471-... | lld:pubmed |
| pubmed-article:3516471 | pubmed:meshHeading | pubmed-meshheading:3516471-... | lld:pubmed |
| pubmed-article:3516471 | pubmed:meshHeading | pubmed-meshheading:3516471-... | lld:pubmed |
| pubmed-article:3516471 | pubmed:meshHeading | pubmed-meshheading:3516471-... | lld:pubmed |
| pubmed-article:3516471 | pubmed:meshHeading | pubmed-meshheading:3516471-... | lld:pubmed |
| pubmed-article:3516471 | pubmed:meshHeading | pubmed-meshheading:3516471-... | lld:pubmed |
| pubmed-article:3516471 | pubmed:meshHeading | pubmed-meshheading:3516471-... | lld:pubmed |
| pubmed-article:3516471 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:3516471 | pubmed:articleTitle | Leu-M2 (Mac-120) is a platelet antigen and is not constitutively expressed by macrophages. | lld:pubmed |
| pubmed-article:3516471 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3516471 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
