Linked Life Data

3514832

Source:http://linkedlifedata.com/resource/pubmed/id/3514832

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-5-13
pubmed:abstractText
It has been shown that milk derived from mothers with term infants is not optimal for premature babies. There is also concern about the effect of heat sterilizing breast milk. At Baragwanath Hospital, the majority of mothers remain with and care for their premature babies. Over many years, pooled pasteurized breast milk has been fed to these babies before direct breast feeding is instituted. A study was done to compare feeding pooled pasteurized breast milk and untreated own mother's milk to very low birth weight babies. There was a significantly more rapid weight gain both in terms of regaining birth weight and, from this point, to reaching a weight of 1,800 g when using untreated own mother's milk. This occurred in spite of the fact that there was little difference, especially in terms of energy content, between the two types of breast milk. This was due to the fact that the pooled pasteurized milk was also largely obtained from mothers of premature babies. It is suggested from our data that slower weight gain in the group receiving the pooled pasteurized milk could be due to the pasteurization, which probably destroys heat-labile milk lipase.
pubmed:keyword
http://linkedlifedata.com/resource/pubmed/keyword/ANTHROPOMETRY, http://linkedlifedata.com/resource/pubmed/keyword/Africa, http://linkedlifedata.com/resource/pubmed/keyword/Africa South Of The Sahara, http://linkedlifedata.com/resource/pubmed/keyword/Age Factors, http://linkedlifedata.com/resource/pubmed/keyword/Biology, http://linkedlifedata.com/resource/pubmed/keyword/Birth Weight, http://linkedlifedata.com/resource/pubmed/keyword/Body Weight, http://linkedlifedata.com/resource/pubmed/keyword/CHILD DEVELOPMENT, http://linkedlifedata.com/resource/pubmed/keyword/Demographic Factors, http://linkedlifedata.com/resource/pubmed/keyword/Developing Countries, http://linkedlifedata.com/resource/pubmed/keyword/English Speaking Africa, http://linkedlifedata.com/resource/pubmed/keyword/Examinations And Diagnoses, http://linkedlifedata.com/resource/pubmed/keyword/Fetus, http://linkedlifedata.com/resource/pubmed/keyword/GROWTH, http://linkedlifedata.com/resource/pubmed/keyword/Gestational Age, http://linkedlifedata.com/resource/pubmed/keyword/Health, http://linkedlifedata.com/resource/pubmed/keyword/Hematologic Tests, http://linkedlifedata.com/resource/pubmed/keyword/Human Milk, http://linkedlifedata.com/resource/pubmed/keyword/Infant, http://linkedlifedata.com/resource/pubmed/keyword/Infant, Premature, http://linkedlifedata.com/resource/pubmed/keyword/Infant Nutrition, http://linkedlifedata.com/resource/pubmed/keyword/Laboratory Examinations And Diagnoses, http://linkedlifedata.com/resource/pubmed/keyword/Laboratory Procedures, http://linkedlifedata.com/resource/pubmed/keyword/Lactation, http://linkedlifedata.com/resource/pubmed/keyword/Low Birth Weight, http://linkedlifedata.com/resource/pubmed/keyword/Maternal Physiology, http://linkedlifedata.com/resource/pubmed/keyword/Measurement, http://linkedlifedata.com/resource/pubmed/keyword/Nutrition, http://linkedlifedata.com/resource/pubmed/keyword/Physiology, http://linkedlifedata.com/resource/pubmed/keyword/Population, http://linkedlifedata.com/resource/pubmed/keyword/Population Characteristics, http://linkedlifedata.com/resource/pubmed/keyword/Pregnancy, http://linkedlifedata.com/resource/pubmed/keyword/Reproduction, http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology, http://linkedlifedata.com/resource/pubmed/keyword/SOUTH AFRICA, http://linkedlifedata.com/resource/pubmed/keyword/Southern Africa, http://linkedlifedata.com/resource/pubmed/keyword/Supplementary Feeding, http://linkedlifedata.com/resource/pubmed/keyword/Youth
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0277-2116
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
242-7
pubmed:dateRevised
2008-11-21
pubmed:otherAbstract
PIP: Researchers in South Africa conducted a randomized controlled clinical trial to compare weight gain in 68 very low birth weight neonates (1000-1500 g) fed either pooled pasteurized breast milk or untreated own mother's milk. At 96 hours, the neonates entered the trial with 3 hourly gavage feeds of 90-100 ml/kg/day and were increased in increments of 15 ml/kg/day, as tolerated, to a maximum feed of 200 ml/kg/day. When an infant's weight increased to 1500-1600 kg, bottle feeding began, if the infant could suck. Once the infant weighed 1800 kg, he dropped out of the trial and began to breast feed. Beginning with the 10th day of life, all infants received iron, ascorbic acid, and vitamin D. In addition, nurses injected all neonates with vitamin K at birth. At 5 days, no differences existed in energy content or protein and fat concentration of pool 1 milk (from mothers with neonates in the special care wards where babies were still gavage fed) and own mother's milk. Pool 1 milk did have significantly more lactose than own mother's milk (p=.006), however. At 19 days, own mother's milk had significantly more fat than pool 1 milk (p=.04). At 33 days, pool 2 milk (from mothers with low birth weight neonates in the common ward) contained significantly more lactose than own mother's milk (p=.009). There were no significant differences between the 2 groups, however, in energy, sodium and potassium contents. Those infants fed own mother's milk gained weight more quickly than those who had pooled pasteurized milk (mean weight gain=16 g/day). Further, infants on own mother's milk regained their birth weight sooner, reached 1800 g sooner, and had a faster growth rate than those on pooled pasteurized milk (p.0001). The researchers believe pasteurization accounts for the difference in weight gain by destroying milk lipases which enhance fat absorption. Even though serum vitamin E values were similar on entry to the trial in both groups, they increased significantly for the group fed own mother's milk at 19 and 33 days (p.0001 and p=.006 respectively).
pubmed:meshHeading
pubmed:articleTitle
Pooled pasteurized breast milk and untreated own mother's milk in the feeding of very low birth weight babies: a randomized controlled trial.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't