rdf:type |
|
lifeskim:mentions |
umls-concept:C0006826,
umls-concept:C0021083,
umls-concept:C0025202,
umls-concept:C0031928,
umls-concept:C0042214,
umls-concept:C0205390,
umls-concept:C0543467,
umls-concept:C1257890,
umls-concept:C1522673,
umls-concept:C1711190,
umls-concept:C2603343
|
pubmed:issue |
3
|
pubmed:dateCreated |
1986-4-9
|
pubmed:abstractText |
Forty-eight patients with nonrecurrent high risk Stage I and II malignant melanoma were treated with Vaccinia Melanoma Oncolysates (VMO). Six different dose levels and two different treatment regimens were tested. Thirty-two out of 48 patients completed the 12 months of therapy. Side effects were mild to moderate. Twenty-eight out of 48 patients remain free from disease with a mean survival of 19 months, while 20/48 patients have recurred with a mean time to recurrence of 6 months.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0003-1348
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
52
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
148-51
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3513682-Adjuvants, Immunologic,
pubmed-meshheading:3513682-Adolescent,
pubmed-meshheading:3513682-Adult,
pubmed-meshheading:3513682-Aged,
pubmed-meshheading:3513682-Antigens, Viral,
pubmed-meshheading:3513682-Clinical Trials as Topic,
pubmed-meshheading:3513682-Combined Modality Therapy,
pubmed-meshheading:3513682-Female,
pubmed-meshheading:3513682-Humans,
pubmed-meshheading:3513682-Immunotherapy,
pubmed-meshheading:3513682-Male,
pubmed-meshheading:3513682-Melanoma,
pubmed-meshheading:3513682-Middle Aged,
pubmed-meshheading:3513682-Skin Neoplasms,
pubmed-meshheading:3513682-Vaccinia virus,
pubmed-meshheading:3513682-Viral Vaccines
|
pubmed:year |
1986
|
pubmed:articleTitle |
A phase I/II SECSG (Southeastern Cancer Study Group) pilot study of surgical adjuvant immunotherapy with vaccinia melanoma oncolysates (VMO).
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial
|