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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1978-8-14
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pubmed:abstractText |
A 2-yr-old girl with a nonsyphilitic type of paroxysmal cold hemoglobinuria (PCH) is reported. We applied the plaque-forming cell (PFC) assay to the measurement of Donath-Landsteiner (DL) antibody-producing cells in the patient. Some of the circulating B lymphocytes formed plaques in our assay system. Initially the number of PFC was 1442 +/- 225/10(6) lymphocytes and DL titer was 1:16. Thereafter the PFC decreased in number as the DL titer decreased. Eight weeks later circulating PFC were not found but the DL titer was still 1:1 positive. The PFC assay appears to be useful as a new method for obtaining rapid imformation as to the disease status of PCH.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
|
pubmed:issn |
0006-4971
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
97-101
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:350317-Antibody-Producing Cells,
pubmed-meshheading:350317-B-Lymphocytes,
pubmed-meshheading:350317-Child, Preschool,
pubmed-meshheading:350317-Female,
pubmed-meshheading:350317-Hemoglobinuria, Paroxysmal,
pubmed-meshheading:350317-Hemolytic Plaque Technique,
pubmed-meshheading:350317-Humans
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pubmed:year |
1978
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pubmed:articleTitle |
Measurement of Donath-Landsteiner antibody-producing cells in idiopathic nonsyphilitic paroxysmal cold hemoglobinuria (PCH) in children.
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pubmed:publicationType |
Journal Article,
Case Reports
|