rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
1988-10-27
|
pubmed:abstractText |
S. aureus Cowan-induced proliferation of human T lymphocytes was used as a model for evaluating the activity of most common immunosuppressants (steroids, cyclosporine and azathioprine). Methylprednisolone was found to be the most efficient steroid, followed by hydrocortisone and dexamethasone. Cyclosporine (CsA) was a potent inhibitor acting early after B cell stimulation. Azathioprine was found to have low effect on B cell activation.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0004-069X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
35
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
651-5
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3502685-Azathioprine,
pubmed-meshheading:3502685-B-Lymphocytes,
pubmed-meshheading:3502685-Cyclosporins,
pubmed-meshheading:3502685-Dexamethasone,
pubmed-meshheading:3502685-Humans,
pubmed-meshheading:3502685-Immunosuppressive Agents,
pubmed-meshheading:3502685-Lymphocyte Activation,
pubmed-meshheading:3502685-Methylprednisolone,
pubmed-meshheading:3502685-Models, Biological,
pubmed-meshheading:3502685-Staphylococcal Protein A
|
pubmed:year |
1987
|
pubmed:articleTitle |
S. aureus-induced B cell proliferation as a model for studying the effectiveness of immunosuppressive agents.
|
pubmed:affiliation |
Department of Experimental Immunosuppression, Medical Academy, Warsaw.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|