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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1988-9-1
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pubmed:abstractText |
One KE of streptococcal preparation OK-432 (PIC) was given orally to 6-week old male Wistar-Imamichi rats twice weekly, and control animals received comparable volumes of saline alone. Samples of thoracic duct lymph and posterior vena caval blood were collected prior to and 4 and 8 weeks following PIC. The T cell count of thoracic duct lymphocytes was about three times greater than that of venous blood specimens, and increased significantly in animals following PIC. Controls showed only a slight increase followed by a decrease, so that by 8 weeks of treatment with PIC, the thoracic duct T cell count revealed a significantly greater number in the PIC group than in the controls. In addition, after 8 weeks the per cent T cell subpopulation in thoracic duct lymph increased significantly in the treated group, but it declined in the control group. Concerning T cell subsets in thoracic duct lymphocytes, the percentage of suppressor/cytotoxic T cells showed a significant elevation in the control group after 4 weeks compared with the treated group. No other blood or lymph variables reached statistical significance in this respect.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0385-0005
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
159-65
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:3502615-Administration, Oral,
pubmed-meshheading:3502615-Animals,
pubmed-meshheading:3502615-Biological Agents,
pubmed-meshheading:3502615-Leukocyte Count,
pubmed-meshheading:3502615-Male,
pubmed-meshheading:3502615-Picibanil,
pubmed-meshheading:3502615-Rats,
pubmed-meshheading:3502615-Rats, Inbred Strains,
pubmed-meshheading:3502615-T-Lymphocytes,
pubmed-meshheading:3502615-Thoracic Duct
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pubmed:year |
1987
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pubmed:articleTitle |
Effects of oral administration of streptococcal preparation OK-432 on thoracic duct lymphocytes.
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pubmed:affiliation |
Department of Surgery, Tokai University Oiso Hospital, Japan.
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pubmed:publicationType |
Journal Article
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