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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1988-5-6
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pubmed:abstractText |
It was demonstrated that human, recombinant Il-1 significantly inhibited formation of autologous rosettes by thymocytes. In addition, Il-1 increased the percentage of thymocytes resistant to hydrocortisone. Il-2 was not active in both tests. A new method of determination of Il-1 activity, based on the inhibition of the autologous rosette formation by Il-1 is described. The activity of Il-1 in the supernatant from macrophage cultures, stimulated with carbonyl iron powder, was calculated. The lack of Il-2 interference and no necessity to handle radioactive materials, are the advantages of the new method.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0004-069X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
35
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
371-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3502240-Animals,
pubmed-meshheading:3502240-Biological Assay,
pubmed-meshheading:3502240-Drug Resistance,
pubmed-meshheading:3502240-Erythrocytes,
pubmed-meshheading:3502240-Female,
pubmed-meshheading:3502240-Hydrocortisone,
pubmed-meshheading:3502240-Interleukin-1,
pubmed-meshheading:3502240-Mice,
pubmed-meshheading:3502240-Mice, Inbred CBA,
pubmed-meshheading:3502240-Rosette Formation,
pubmed-meshheading:3502240-T-Lymphocytes
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pubmed:year |
1987
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pubmed:articleTitle |
Interleukin-1 decreases the level of thymocytes forming rosettes with autologous erythrocytes: a new method of determination of interleukin-1 activity.
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pubmed:affiliation |
Institute of Immunology and Experimental Therapy Polish Academy of Sciences, Wroc?aw.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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