Linked Life Data

3502073

Source:http://linkedlifedata.com/resource/pubmed/id/3502073

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1988-4-22
pubmed:abstractText
Clinical, histologic, and immunohistochemical studies were performed in 11 patients suffering from sicca syndrome with extraglandular lymphoid lesions (liver, spleen, lymph nodes and bone). Seven patients proved to have primary Sjögren's syndrome (SS), 3 had non Hodgkin's lymphoma (NHL) with glandular and extraglandular monoclonal B-cell infiltrates, and 1 had diffuse Castleman's disease (CD). Antibodies to nuclear and/or cytoplasmic ribonucleoproteins were found, by immunodiffusion, in sera from all patients with SS (anti-SSA/Ro in 7 cases and anti-SSB/La in 6). No patient with NHL or CD had evidence of circulating antibodies to these antigens as well as other soluble nuclear antigens. Our data suggests that antibodies to SSA/Ro and SSB/la are strongly associated with extraglandular lymphoid lesions in primary SS and may be useful in differentiating this condition from sicca complex with NHL.
pubmed:language
ita
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0021-2547
pubmed:author
pubmed:issnType
Print
pubmed:volume
66
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
297-302
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
[Sicca syndrome associated with systemic lymphoproliferative disease. Clinico-pathologic and serologic profile of 11 cases].
pubmed:affiliation
Dipartimento di Medicina Interna, Università di Pavia.
pubmed:publicationType
Journal Article, English Abstract