Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1988-3-9
|
pubmed:abstractText |
Mitogen-induced T cell blastogenesis was determined in 47 patients with severe alopecia areata, before and after treatment with topical 5% minoxidil, and compared with control values. The group of 36 responders, who demonstrated terminal hair regrowth, showed significantly increased lymphocyte stimulation with concanavalin A and PHA before treatment, which decreased towards control values following hair regrowth. Lymphocytes from non-responders showed no significant differences from controls either before or after treatment. The results suggest that enhanced T cell blastogenesis may predict the response of severe alopecia areata to topical 5% minoxidil therapy.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0007-0963
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
117
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
759-63
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3501310-Adolescent,
pubmed-meshheading:3501310-Adult,
pubmed-meshheading:3501310-Alopecia Areata,
pubmed-meshheading:3501310-Autoantibodies,
pubmed-meshheading:3501310-Child,
pubmed-meshheading:3501310-Female,
pubmed-meshheading:3501310-Humans,
pubmed-meshheading:3501310-Lymphocyte Activation,
pubmed-meshheading:3501310-Male,
pubmed-meshheading:3501310-Middle Aged,
pubmed-meshheading:3501310-Minoxidil,
pubmed-meshheading:3501310-T-Lymphocytes
|
pubmed:year |
1987
|
pubmed:articleTitle |
Response to minoxidil in severe alopecia areata correlates with T lymphocyte stimulation.
|
pubmed:affiliation |
Department of Dermatology, University of Illinois, College of Medicine, Chicago 60680.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|