Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-3
pubmed:dateCreated
1988-1-20
pubmed:abstractText
We recently have reported the immunolocalization of epidermal growth factor (EGF) in mouse kidney by light microscopy. In the present study, we have investigated the ultrastructural localization of EGF by the preembedding immunoperoxidase method for electron microscopy. EGF immunoreactivity was present on the apical plasma membrane of the cells of the thick ascending limb of Henle and the distal convoluted tubule. The macula densa, by contrast, lacked immunoreactivity. Based on functional evidence, a possible regulatory role for EGF in the membrane transport in the distal nephron has been suggested.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0889-1605
pubmed:author
pubmed:issnType
Print
pubmed:volume
96
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
105-13
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
Immunoelectron microscopy of epidermal growth factor in mouse kidney.
pubmed:affiliation
Department of Pathology, Harbor-UCLA Medical Center, Torrance 90509.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.