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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
1988-1-11
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pubmed:abstractText |
Lewis rats immunized with myelin and complete Freund's adjuvant were treated with cobra venom factor (CVF) which depletes the C3 component of complement. CVF given at day 9 delayed the onset of experimental allergic neuritis (EAN) by 2-3 days and when given at days 9 and 12 delayed the onset of EAN by 4-5 days. Lumbar nerve roots of CVF-treated rats had significantly less demyelination than those from control EAN rats.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0006-8993
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
419
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
97-103
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3499953-Animals,
pubmed-meshheading:3499953-Cobra Neurotoxin Proteins,
pubmed-meshheading:3499953-Complement Activation,
pubmed-meshheading:3499953-Complement C3,
pubmed-meshheading:3499953-Freund's Adjuvant,
pubmed-meshheading:3499953-Male,
pubmed-meshheading:3499953-Neuritis, Autoimmune, Experimental,
pubmed-meshheading:3499953-Rats,
pubmed-meshheading:3499953-Rats, Inbred Lew,
pubmed-meshheading:3499953-Spinal Nerve Roots,
pubmed-meshheading:3499953-Time Factors
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pubmed:year |
1987
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pubmed:articleTitle |
Complement depletion suppresses Lewis rat experimental allergic neuritis.
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pubmed:affiliation |
Department of Clinical Neurological Sciences, University of Western Ontario, London, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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