rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
1987-11-9
|
pubmed:abstractText |
Changes of RNP and Sm antigenic reactivities of a nuclear extract after enzymatic treatments were studied and quantified by the ELISA test. After RNase treatment of the nuclear extract, about a 300% increase of the Sm antigenic reactivity and more than a 95% decrease of RNP antigenic reactivity was found. Data from RNP-depleted nuclear extracts and column fractionation show that the increase in Sm antigenic reactivity after RNase treatment mainly comes from the RNP-Sm complex.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0161-5890
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
24
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
615-9
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:3498883-Antibodies, Antinuclear,
pubmed-meshheading:3498883-Autoantibodies,
pubmed-meshheading:3498883-Autoantigens,
pubmed-meshheading:3498883-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:3498883-Humans,
pubmed-meshheading:3498883-Ribonucleases,
pubmed-meshheading:3498883-Ribonucleoproteins,
pubmed-meshheading:3498883-Ribonucleoproteins, Small Nuclear,
pubmed-meshheading:3498883-snRNP Core Proteins
|
pubmed:year |
1987
|
pubmed:articleTitle |
Effect of enzymatic treatments on RNP and Sm antigenic reactivities--I. Loss of RNP but increase of Sm antigenic reactivity after RNase treatment of nuclear extract.
|
pubmed:affiliation |
Department of Immunology, Hospital de Sant Pau, Barcelona, Spain.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|