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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1987-10-19
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pubmed:abstractText |
Course and possible prognostic predictors were studied retrospectively in 363 MS patients collected during an epidemiological study. The proportion of patients showing a primarily progressive course was 18%; 19% of patients of more than 10 years duration showed a benign course, and 8% of those of less than 16 years duration, a malignant course. Although benign cases were twice as frequent in females as in males, the difference between both sexes was not significant. A primarily or secondarily progressive course, a high number of functional systems involved and cerebellar signs occurring in the course indicated a poor prognosis whereas symptoms at onset, age at onset as such, and occupation were without predictive value. No predictors of a favourable course were found. Of the patients of 11-15 years duration, 17% were confined to a wheelchair, 40% were restricted to a walking distance of 500 metres or less, 61% were unable to work and 45% had urinary incontinence. The corresponding figures for those of 21-25 years duration were 40%, 71%, 76% and 50%.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0001-6314
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
12-7
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pubmed:dateRevised |
2006-8-16
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pubmed:meshHeading |
pubmed-meshheading:3498287-Adult,
pubmed-meshheading:3498287-Cross-Sectional Studies,
pubmed-meshheading:3498287-Disability Evaluation,
pubmed-meshheading:3498287-Female,
pubmed-meshheading:3498287-Follow-Up Studies,
pubmed-meshheading:3498287-Germany, West,
pubmed-meshheading:3498287-Humans,
pubmed-meshheading:3498287-Male,
pubmed-meshheading:3498287-Multiple Sclerosis,
pubmed-meshheading:3498287-Optic Neuritis
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pubmed:year |
1987
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pubmed:articleTitle |
Epidemiological investigations into multiple sclerosis in Southern Hesse. V. Course and prognosis.
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pubmed:publicationType |
Journal Article
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