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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1987-10-1
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pubmed:abstractText |
A clear lens extraction with insertion of a posterior chamber intraocular lens (PC-IOL) was performed in one eye of each of 20 rabbits. An intracameral injection of 50,000 organisms of gentamicin-sensitive Staphylococcus aureus was given before completion of the surgical procedure. At the completion of surgery, a subconjunctival injection of either gentamicin (20 mg) or gentamicin vehicle was administered randomly, in a masked fashion, to the operative eye. Rabbits were observed daily for signs of endophthalmitis. Vitreous taps were performed on all operative eyes. Ninety percent (p = .001) of control eyes became clinically infected and 80% (p = .007) of control eyes grew S. aureus from their vitreous aspirate. None of the gentamicin-treated eyes became clinically or microbiologically infected with S. aureus.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0022-023X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
538-41
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:3498139-Animals,
pubmed-meshheading:3498139-Aphakia, Postcataract,
pubmed-meshheading:3498139-Cataract Extraction,
pubmed-meshheading:3498139-Endophthalmitis,
pubmed-meshheading:3498139-Gentamicins,
pubmed-meshheading:3498139-Lenses, Intraocular,
pubmed-meshheading:3498139-Rabbits,
pubmed-meshheading:3498139-Staphylococcal Infections,
pubmed-meshheading:3498139-Staphylococcus aureus
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pubmed:year |
1987
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pubmed:articleTitle |
Inhibition of pseudophakic endophthalmitis in a rabbit model.
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pubmed:publicationType |
Journal Article
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