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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
1987-10-22
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pubmed:abstractText |
Two children with lupus erythematosus and myelopathy were studied. The first child developed the neonatal lupus erythematosus syndrome associated with transplacentally acquired anti-Ro/SSA antibodies. The cutaneous manifestations of neonatal lupus erythematosus disappeared but a residual myelopathy was confirmed at 16 months of age. The second child developed cutaneous lupus erythematosus at 3 months of age associated with a total deficiency of the Clr component of complement. A myelopathy and mesangial glomerulonephritis developed at 2 years of age which required treatment with corticosteroids. These two children with CNS lupus erythematosus, one associated with transplacentally acquired antibodies and the other associated with a complement deficiency, may suggest an immune-mediated mechanism for the pathogenesis of myelopathy in childhood lupus erythematosus.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-1091976,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-1159591,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-263907,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-339232,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-3878714,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-3880599,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-3913360,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-3977359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-424765,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-434854,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-455010,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-5638537,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-6201849,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-6315788,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-634689,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-6390081,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-6866034,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-7102670,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-7104053,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-7134990,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-7175846,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-7193689,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-7317116,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-737019,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3498010-781466
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0022-3050
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
923-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:3498010-Antibodies, Antinuclear,
pubmed-meshheading:3498010-Child, Preschool,
pubmed-meshheading:3498010-Female,
pubmed-meshheading:3498010-Humans,
pubmed-meshheading:3498010-Infant,
pubmed-meshheading:3498010-Infant, Newborn,
pubmed-meshheading:3498010-Lupus Erythematosus, Cutaneous,
pubmed-meshheading:3498010-Male,
pubmed-meshheading:3498010-Muscular Diseases
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pubmed:year |
1987
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pubmed:articleTitle |
Myelopathy in neonatal and infantile lupus erythematosus.
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pubmed:publicationType |
Journal Article,
Case Reports
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