Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1987-10-20
pubmed:abstractText
Immune responses were analyzed after neocortex ablation in mice. The neocortex ablations were performed in inbred mice on the left (ALN) or right hemisphere (ARN) separately. Two months later immunological parameters were tested. The results showed that the mitogenesis induced by Con A, natural killer cell (NK) cytotoxicity, production of IL-1 and IL-2 as well as the reactivity to IL-1 were all suppressed in ALN mice but stimulated in ARN mice compared to sham-operated controls. The primary antibody response to sheep red blood cells (SRBC) was also enhanced in ARN but not ALN mice. These results indicate that there may be a different regulatory effect on the immune system mediated by the different brain hemispheres, a phenomenon named lateralization of brain.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0882-0139
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
87-96
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Immunoregulatory effect of neocortex in mice.
pubmed:publicationType
Journal Article, Comparative Study