Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1987-8-28
pubmed:abstractText
Adriamycin (ADR), 4-hydroperoxycyclophosphamide (4-OOHCYP) and the new cyclophosphamide derivative AZ 7557 (AZ) were tested for their effects on the release of the Interleukins IL-2 and IL-1 from rat spleen cells and peritoneal exudate macrophages respectively. ADR was found to enhance IL-2 release and less effectively IL-1 release. 4-OOHCYP and AZ were found to inhibit IL-2 release but had no effect on IL-1 production. It is suggested that the modulation of IL-2 levels by these drugs is unlikely to be mediated by their effects on IL-1.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0192-0561
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
355-61
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Effects of adriamycin, 4-hydroperoxycyclophosphamide and ASTA Z 7557 (INN mafosfamide) on the release of IL-2 and IL-1 in vitro.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't