Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1987-5-26
pubmed:abstractText
Rats of five different strains were injected intravenously with live Yersinia enterocolitica O:8 or Yersinia pseudotuberculosis III. Twelve to 18 days after inoculation of Y. enterocolitica O:8, arthritic symptoms appeared in the hindpaws of SHR rats. They started with erythema, followed by swelling and painful movement, closely resembling findings in adjuvant arthritis. Histologically, the inflammation was dominated by neutrophils in two cases, whereas in two others the inflammatory cells were predominantly lymphocytes. Two of five rats yielded positive bacterial cultures from the joints. Altogether, arthritis was observed in five of nine SHR surviving beyond day 14 after the bacterial inoculation. Rats of Lewis, Wistar, WKY and Zucker strains did not develop any signs of arthritis after intravenous injection of Y. enterocolitica or pseudotuberculosis. Also in the SHR rats, Y. pseudotuberculosis failed to induce arthritis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0108-0202
pubmed:author
pubmed:issnType
Print
pubmed:volume
94
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
261-9
pubmed:dateRevised
2009-6-4
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Yersinia-associated arthritis in the rat: experimental model for human reactive arthritis?
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't