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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1987-3-16
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pubmed:abstractText |
We studied the clinical features and prognosis of 73 patients with HLA-B27 positive and 71 patients with HLA-B27 negative acute anterior uveitis using computer analysis of more than 50 variables per patient. The patients with HLA-B27 positive acute anterior uveitis showed the following characteristics which were significantly different from patients with HLA-B27 negative acute anterior uveitis: younger age at onset; high male to female ratio; frequent unilateral alternating eye involvement; severe ocular symptoms during activity, such as presence of fibrin in the anterior chamber; absence of mutton fat keratic precipitates; high incidence of ocular complications; and frequent association with seronegative spondyloarthropathies. Despite the difference of disease severity and incidence of complications, the long-term visual outcome did not differ significantly between the two groups. No distinctions were observed when patients with HLA-B27 positive acute anterior uveitis were subdivided according to sex or the presence of ankylosing spondylitis. HLA-B27 positive acute anterior uveitis formed a distinct clinical entity associated with serious prognosis as compared to HLA-B27 negative acute anterior uveitis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0002-9394
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
103
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
137-45
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3492916-Acute Disease,
pubmed-meshheading:3492916-Adult,
pubmed-meshheading:3492916-Eye Diseases,
pubmed-meshheading:3492916-Female,
pubmed-meshheading:3492916-HLA Antigens,
pubmed-meshheading:3492916-HLA-B27 Antigen,
pubmed-meshheading:3492916-Humans,
pubmed-meshheading:3492916-Male,
pubmed-meshheading:3492916-Middle Aged,
pubmed-meshheading:3492916-Prognosis,
pubmed-meshheading:3492916-Recurrence,
pubmed-meshheading:3492916-Sarcoidosis,
pubmed-meshheading:3492916-Spondylitis, Ankylosing,
pubmed-meshheading:3492916-Uveitis, Anterior
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pubmed:year |
1987
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pubmed:articleTitle |
Clinical features of acute anterior uveitis.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|