Linked Life Data

3491095

Source:http://linkedlifedata.com/resource/pubmed/id/3491095

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5 Pt 1
pubmed:dateCreated
1987-1-7
pubmed:abstractText
Different parameters of cell-mediated immunity, including natural cytotoxic reactions, were studied in nine patients with epidermodysplasia verruciformis with or without cutaneous malignancy. We found decreased total number of T lymphocytes and T-helper cells in peripheral blood of the patients, and normal T-suppressor cell number, as detected by monoclonal antibody typing and functional E-rosette test with the use of theophylline. This decrease was found both in active and in late rosette-forming cell subpopulations. Natural killer cell activity of peripheral blood mononuclear cells was found to be increased in four of nine patients with epidermodysplasia verruciformis, whereas antibody-dependent cellular cytotoxicity was within the normal range in all patients studied. Lymphocyte-induced angiogenesis assay, which is a sensitive test for the estimation of the immunocompetence of lymphoid cells, revealed increased angiogenic capability of peripheral blood mononuclear cells in the majority of the patients. Our results suggest that cellular defects in patients with epidermodysplasia verruciformis did not relate to all functions of the immune system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0190-9622
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
966-73
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Partial defects of cell-mediated immunity in patients with epidermodysplasia verruciformis.
pubmed:publicationType
Journal Article, Comparative Study