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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1986-12-11
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pubmed:abstractText |
Androgen receptors were partially purified by affinity chromatography of cytosols prepared from either normal foreskins or normal cultured fibroblasts. Partially purified receptors were covalently labelled with [3H]R1881 (tritiated methyltrienolone) by ultraviolet photoactivation. Gel electrophoresis of cytosols from both sources showed two peaks of specific binding, Mr approximately 40 K and approximately 85 K, under denaturing conditions. Photoaffinity labelling of the human androgen receptor may thus provide a useful tool in further studies on disorders of androgenization.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-4731
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
355-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3490602-Affinity Labels,
pubmed-meshheading:3490602-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:3490602-Estrenes,
pubmed-meshheading:3490602-Fibroblasts,
pubmed-meshheading:3490602-Genitalia, Male,
pubmed-meshheading:3490602-Humans,
pubmed-meshheading:3490602-Male,
pubmed-meshheading:3490602-Metribolone,
pubmed-meshheading:3490602-Molecular Weight,
pubmed-meshheading:3490602-Photochemistry,
pubmed-meshheading:3490602-Receptors, Androgen
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pubmed:year |
1986
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pubmed:articleTitle |
Photoaffinity labelling of androgen receptors from human foreskin and cultured genital fibroblasts with tritiated methyltrienolone [3H]R1881.
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pubmed:publicationType |
Journal Article
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