Linked Life Data

3490570

Source:http://linkedlifedata.com/resource/pubmed/id/3490570

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1986-12-3
pubmed:abstractText
Endocrine studies were performed on two genetic females with 17 alpha-hydroxylase deficiency. Both patients had primary amenorrhea and no development of secondary sexual characteristics. One patient had only mild hypertension, whereas the second had severe hypertension. Both patients had increased levels of progesterone. Their levels of 17-hydroxyprogesterone and all other steroids that require 17-hydroxylation were low. The gonadotropin levels were in the menopausal range. Ovarian biopsy revealed follicles in various stages of development; many were cystic. Combined glucocorticoid and estrogen therapy resulted in breast development and lowering of blood pressure. Development of pubic hair occurred only after testosterone therapy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0024-7758
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
734-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
17 alpha-hydroxylase deficiency in genetic females. A report of two cases.
pubmed:publicationType
Journal Article, Case Reports