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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1986-12-11
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pubmed:abstractText |
Corticotropin-releasing factor (CRF) stimulates the synthesis and release of adrenocorticotropin in the anterior pituitary and may help maintain fluid and electrolyte balance. 'Salt-loaded' rats had an increase in CRF mRNA in hypothalamic magnocellular neurons of the paraventricular and supraoptic nuclei and a decrease in message in the parvocellular paraventricular neurons. After salt-loaded rats were adrenalectomized, CRF mRNA increased in the parvocellular cells. In contrast to salt loading, water deprivation lead to a decrease in CRF mRNA in magnocellular and parvocellular neurons. These results show that CRF synthesis within separate populations of hypothalamic neurons is regulated differently under various conditions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0014-5793
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
208
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
158-62
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3490404-Adrenalectomy,
pubmed-meshheading:3490404-Animals,
pubmed-meshheading:3490404-Corticotropin-Releasing Hormone,
pubmed-meshheading:3490404-Dehydration,
pubmed-meshheading:3490404-Hypothalamus,
pubmed-meshheading:3490404-Male,
pubmed-meshheading:3490404-Paraventricular Hypothalamic Nucleus,
pubmed-meshheading:3490404-RNA, Messenger,
pubmed-meshheading:3490404-Rats,
pubmed-meshheading:3490404-Rats, Inbred Strains,
pubmed-meshheading:3490404-Sodium Chloride,
pubmed-meshheading:3490404-Water-Electrolyte Balance
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pubmed:year |
1986
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pubmed:articleTitle |
Corticotropin-releasing factor mRNA in the hypothalamus is affected differently by drinking saline and by dehydration.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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