Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1986-11-10
pubmed:abstractText
Tomographic reconstruction for single photon emission computed tomography (SPECT) with simultaneous compensation for attenuation, scatter, and distance dependent collimator resolution is provided by an Inverse Monte Carlo (IMOC) reconstruction algorithm. A detection probability matrix is formed by Monte Carlo solution to the photon transport equation for SPECT acquisition from a unit source activity in each reconstruction source voxel. The measured projection vector will equal the product of this detection probability matrix with the unknown source distribution vector. The resulting large, nonsparse system of equations is solved for the source distribution using an iterative Maximum Likelihood EM estimator. Reconstruction of experimentally acquired projections from phantoms shows quantitative compensation for scatter and attenuation. Comparison with filtered backprojection (FBP) reconstruction shows an improvement in resolution recovery, contrast, and signal-to-noise for the IMOC algorithm. Reconstruction of clinical studies shows improved contrast, structural resolution, and noise characteristics.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0161-5505
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1577-85
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Inverse Monte Carlo as a unified reconstruction algorithm for ECT.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.