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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1986-4-1
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pubmed:abstractText |
Susceptibilities to beta-lactam antibiotics and beta-lactamase content of two groups of Bacteroides strains were compared. Type cultures produced low levels of beta-lactamase and were susceptible to cefoxitin, latamoxef, imipenem and the combination of benzylpenicillin and clavulanic acid. Other Bacteroides strains that produced higher levels of beta-lactamase were generally less susceptible to these antibiotics; this resistance was more closely related to enzyme type than to the amount of enzyme present. The beta-lactamases produced by the test strains fell into three broad groups on the basis of antibiotic degradation and inhibitor profiles: those that inactivated benzylpenicillin, but not cefoxitin, latamoxef or imipenem, and were susceptible to inhibition by beta-lactamase inhibitors; those that hydrolysed benzylpenicillin, cefoxitin and latamoxef, but not imipenem, and which were less susceptible to inhibition by beta-lactamase inhibitors; an enzyme that inactivated all the antibiotics and was not inhibited by beta-lactamase inhibitors.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cefoxitin,
http://linkedlifedata.com/resource/pubmed/chemical/Cephalosporins,
http://linkedlifedata.com/resource/pubmed/chemical/Imipenem,
http://linkedlifedata.com/resource/pubmed/chemical/Moxalactam,
http://linkedlifedata.com/resource/pubmed/chemical/Thienamycins,
http://linkedlifedata.com/resource/pubmed/chemical/beta-Lactamases,
http://linkedlifedata.com/resource/pubmed/chemical/nitrocefin
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-2615
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
49-57
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pubmed:dateRevised |
2000-12-18
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pubmed:meshHeading |
pubmed-meshheading:3485198-Bacteroides fragilis,
pubmed-meshheading:3485198-Cefoxitin,
pubmed-meshheading:3485198-Cephalosporins,
pubmed-meshheading:3485198-Drug Resistance, Microbial,
pubmed-meshheading:3485198-Imipenem,
pubmed-meshheading:3485198-Isoelectric Point,
pubmed-meshheading:3485198-Kinetics,
pubmed-meshheading:3485198-Microbial Sensitivity Tests,
pubmed-meshheading:3485198-Moxalactam,
pubmed-meshheading:3485198-Nephelometry and Turbidimetry,
pubmed-meshheading:3485198-Thienamycins,
pubmed-meshheading:3485198-beta-Lactamases
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pubmed:year |
1986
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pubmed:articleTitle |
Beta-lactamases of type culture strains of the Bacteroides fragilis group and of strains that hydrolyse cefoxitin, latamoxef and imipenem.
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pubmed:publicationType |
Journal Article
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