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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1986-1-17
|
| pubmed:abstractText |
Thirty-five patients with peripheral arterial occlusions were treated by intraarterial infusion of low-dose urokinase associated with bolus of lys-plasminogen. Thrombolysis was achieved in 26 cases (74%), but only 10 patients (28.5%) experienced sustained improvement. Complications of thrombolysis occurred in 11 patients: Five patients developed groin hematoma, five had distal emboli, and one experienced macroscopic hematuria. Catheter-related thrombosis was observed in 14 patients (40%) despite intravenous heparin. Nine patients suffered from recurrent thrombosis and three from proximal emboli. A patient died from catheter-related infection. Limited fibrinolysis could increase pericatheter thrombosis, and further work will be necessary to assess the local risk of intraarterial thrombolysis.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0361-803X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
146
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
157-9
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:3484402-Adult,
pubmed-meshheading:3484402-Aged,
pubmed-meshheading:3484402-Arteriosclerosis,
pubmed-meshheading:3484402-Catheterization,
pubmed-meshheading:3484402-Embolism,
pubmed-meshheading:3484402-Female,
pubmed-meshheading:3484402-Hematoma,
pubmed-meshheading:3484402-Hematuria,
pubmed-meshheading:3484402-Humans,
pubmed-meshheading:3484402-Infection,
pubmed-meshheading:3484402-Infusions, Intra-Arterial,
pubmed-meshheading:3484402-Leg,
pubmed-meshheading:3484402-Male,
pubmed-meshheading:3484402-Middle Aged,
pubmed-meshheading:3484402-Peptide Fragments,
pubmed-meshheading:3484402-Plasminogen,
pubmed-meshheading:3484402-Retrospective Studies,
pubmed-meshheading:3484402-Risk,
pubmed-meshheading:3484402-Thrombosis,
pubmed-meshheading:3484402-Urokinase-Type Plasminogen Activator
|
| pubmed:year |
1986
|
| pubmed:articleTitle |
Complications of intraarterial urokinase-lys-plasminogen infusion therapy in arterial ischemia of lower limbs.
|
| pubmed:publicationType |
Journal Article
|