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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1978-7-24
|
| pubmed:abstractText |
Microviscosity (eta) of the plasma-membrane lipid matrix was measured in exponentially growing and differentiating C1300 mouse neuroblastoma cells, attached to a glass substratum, by fluorescence polarisation of 1,6-diphenyl-1,3,5-hexatriene. Upon differentiation eta decreases progressively, reaching values below those observed in the growth phase. Treatment of the cells with dipalmitoyl phosphatidylcholine vesicles reversibly inhibits morphological differentiation. The results show that a high membrane fluidity is a prerequisite for differentiation.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0006-3002
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
4
|
| pubmed:volume |
509
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
188-93
|
| pubmed:dateRevised |
2000-12-18
|
| pubmed:meshHeading |
pubmed-meshheading:348237-Cell Differentiation,
pubmed-meshheading:348237-Cell Line,
pubmed-meshheading:348237-Cell Membrane,
pubmed-meshheading:348237-Microscopy, Phase-Contrast,
pubmed-meshheading:348237-Neuroblastoma,
pubmed-meshheading:348237-Spectrometry, Fluorescence,
pubmed-meshheading:348237-Temperature,
pubmed-meshheading:348237-Viscosity
|
| pubmed:year |
1978
|
| pubmed:articleTitle |
Microviscosity changes during differentiation of neuroblastoma cells.
|
| pubmed:publicationType |
Journal Article
|