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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1988-4-1
|
| pubmed:abstractText |
In a cytogenetic study of 54 patients with acute monoblastic leukaemias (AML5) two had a (9;11) (p21;q23) translocation. In addition to the clone, with t(9;11), both patients had a second clone with t(9;11) and trisomy 8. These two patients were aged 23 and 35 years at diagnosis and were classified as M5a in the FAB formulation. A complete remission was achieved in each case, persisting after 19 and 18 months respectively (autograft for one patient). Whereas chromosome 11 anomalies are involved in 13% of all AML5 cases, t(9;11) is less frequently encountered (3.7% in our experience).
|
| pubmed:language |
fre
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:author | |
| pubmed:volume |
29
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
303-6
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3481440-Adult,
pubmed-meshheading:3481440-Chromosome Banding,
pubmed-meshheading:3481440-Chromosomes, Human, Pair 11,
pubmed-meshheading:3481440-Chromosomes, Human, Pair 8,
pubmed-meshheading:3481440-Chromosomes, Human, Pair 9,
pubmed-meshheading:3481440-Female,
pubmed-meshheading:3481440-Humans,
pubmed-meshheading:3481440-Karyotyping,
pubmed-meshheading:3481440-Leukemia, Monocytic, Acute,
pubmed-meshheading:3481440-Male,
pubmed-meshheading:3481440-Translocation, Genetic,
pubmed-meshheading:3481440-Trisomy
|
| pubmed:year |
1987
|
| pubmed:articleTitle |
[(9;11) (p21;q23) translocation: apropos of 2 new cases seen in acute undifferentiated monoblastic AML5a leukemia].
|
| pubmed:affiliation |
Service de Génétique, Faculté de Médecine, Lille, France.
|
| pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|