Linked Life Data

3480377

Source:http://linkedlifedata.com/resource/pubmed/id/3480377

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1988-2-17
pubmed:abstractText
A cohort study of 2,103 workers employed between 1942 and 1960 at a uranium mine in the Northwest Territories, Canada, was conducted. A total of 57 lung cancer deaths was observed (expected = 24.73, P less than .0001). There was a highly significant linear relationship between exposure and increased risk of lung cancer, giving estimates for the relative and attributable risk coefficients of 0.27 per working level month (WLM) and 3.10 per WLM per 10(6) person-years. These risk coefficients were substantially less than those estimated from the experience of miners in the Beaverlodge mine, which have previously been reported. Any biases in the present estimates are likely to have been upward, and therefore they probably represent an upper limit. The major difference between the two mine cohorts is in the exposure rate, since the Port Radium miners were exposed to much greater concentrations of radon daughters than the Beaverlodge miners. It is postulated that risk of lung cancer from radon daughter exposure may be modified by exposure rate, for which hypothesis there is some support from other epidemiologic data.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0027-8874
pubmed:author
pubmed:issnType
Print
pubmed:volume
79
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1255-60
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Lung cancer mortality (1950-80) in relation to radon daughter exposure in a cohort of workers at the Eldorado Port Radium uranium mine: possible modification of risk by exposure rate.
pubmed:affiliation
National Cancer Institute of Canada, University of Toronto, Ontario.
pubmed:publicationType
Journal Article