rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
1987-9-9
|
pubmed:abstractText |
In the screening of hematopoietic cell line cell aggregations, the extract of Clerodendron trichotomum seed was found to aggregate K-562 and KG-1 specifically. In the flow cytometric analysis using FITC-conjugated purified CTL, it was confirmed that CTL recognizes the specific carbohydrate(s) which seem to appear only in the early stages of differentiation of myeloid (KG-1) and erythroid (K-562) cell line cells and erythrocytes. The CTL binding to K-562 cells was decreased by TPA treatment which is known to induce retrodifferentiation of K-562. It is also found that this carbohydrate(s) were shaded with NANA on the differentiated cells. In the erythrocyte, CTL receptor was partially shaded by NANA.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0145-2126
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
11
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
603-8
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3475512-Carbohydrate Metabolism,
pubmed-meshheading:3475512-Cell Differentiation,
pubmed-meshheading:3475512-Cell Line,
pubmed-meshheading:3475512-Erythrocytes,
pubmed-meshheading:3475512-Hematopoietic Stem Cells,
pubmed-meshheading:3475512-Humans,
pubmed-meshheading:3475512-Lectins,
pubmed-meshheading:3475512-Leukemia, Myeloid,
pubmed-meshheading:3475512-Leukemia, Myeloid, Acute,
pubmed-meshheading:3475512-Neoplastic Stem Cells,
pubmed-meshheading:3475512-Plant Lectins,
pubmed-meshheading:3475512-Receptors, Mitogen,
pubmed-meshheading:3475512-Tetradecanoylphorbol Acetate
|
pubmed:year |
1987
|
pubmed:articleTitle |
Differentiation-associated carbohydrate chain on human hematopoietic cells recognized by Clerodendron trichotomum lectin.
|
pubmed:publicationType |
Journal Article
|