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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1987-9-21
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pubmed:abstractText |
In the years 1980-1985 72 children with acute lymphoblastic leukemia were diagnosed and treated by intensive combination chemotherapy (BFM protocols 79, 81, 83). Of these children 33 acquired a Hepatitis B-virus-carrier state with 1983 as the peak year of incidence. Both groups of patients, the infected and the uninfected ones, were comparable as to prognostic factors. All except 8 patients are off chemotherapy after a total duration of treatment of 1 1/2 or 2 years. Probability for event-free survival (life table analysis, maximum observation time 82 months, minimum 12 months) is equal (0.77 vs. 0.75) in both groups. With 3 exceptions, all HBV-infected patients still carry the HBs-antigen in the serum; 22 of the 30 living patients in the infected group developed anti-HBc.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0006-5242
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
115-20
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3475137-Acute Disease,
pubmed-meshheading:3475137-Adolescent,
pubmed-meshheading:3475137-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:3475137-Child,
pubmed-meshheading:3475137-Child, Preschool,
pubmed-meshheading:3475137-Female,
pubmed-meshheading:3475137-Follow-Up Studies,
pubmed-meshheading:3475137-Hepatitis B,
pubmed-meshheading:3475137-Hepatitis B Surface Antigens,
pubmed-meshheading:3475137-Hepatitis B e Antigens,
pubmed-meshheading:3475137-Humans,
pubmed-meshheading:3475137-Leukemia, Lymphoid,
pubmed-meshheading:3475137-Male,
pubmed-meshheading:3475137-Prognosis
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pubmed:year |
1987
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pubmed:articleTitle |
No adverse prognostic influence of hepatitis B virus infection in acute childhood lymphoblastic leukemia.
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pubmed:publicationType |
Journal Article
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