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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
1987-6-18
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pubmed:abstractText |
We have examined the process by which small groups of pigmented germinal cells transplanted orthotopically from stage 30-38 donor embryos into stage 28-38 albino hosts contribute new postmitotic cells to the pigmented retinal epithelium of the growing larval eye in Xenopus. In the great majority of chimeric eyes, the transplant healed to occupy a small arc-territory at the intended dorsal or anterior position on the host germinal zone. Over the course of subsequent weeks, the transplanted germinal cells added new mitotically quiescent cells to the distal rim of the pigmented retinal epithelium and so gave rise to an elongating black sector on the growing larval eye. Cellular details at the boundaries of the graft-derived sector were stable over time; the accumulation of such landmarks provided a summary record--in the proximodistal axis of the older eye--of the growth history of the transplant. Case-to-case variation among both groups of transplants suggested a measure of indeterminancy in the details of germinal cell growth.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-1185102,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-1252942,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-2580474,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-3308324,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-3711793,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-3885830,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-3952494,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-3972184,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-5565078,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-5637105,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-6190692,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-6393189,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-6631323,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-7006701,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-7381043,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-7449426,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3472210-759449
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
84
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3302-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1987
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pubmed:articleTitle |
Cell patterning in pigment-chimeric eyes in Xenopus: germinal transplants and their contributions to growth of the pigmented retinal epithelium.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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