Linked Life Data

3470154

Source:http://linkedlifedata.com/resource/pubmed/id/3470154

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1987-5-5
pubmed:abstractText
Ofloxacin is a new oral antibacterial fluoro-quinolone, endowed with potent bactericidal activity over a very broad bacterial spectrum. Ofloxacin's minimum bactericidal concentration (MBC) proved to be equal to the minimum inhibitory concentration (MIC) even at high inocula or in the presence of human serum with a high bactericidal rate. The effect of the presence of urine was that the bacteria were sensitive to higher drug concentrations, as in the case of other quinolones; these concentrations, however, are easily reached in the urinary tract after a single therapeutic dose in man. Ofloxacin proved to be extremely effective in curing experimental infections induced by both gram-positive and gram-negative pathogens.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0392-906X
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
23-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Ofloxacin: in vitro and in vivo activity.
pubmed:publicationType
Journal Article, Comparative Study