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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1987-5-7
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pubmed:abstractText |
We designed a treatment program to improve the outcome for adults with acute lymphoblastic leukemia (ALL). Treatment included a remission-induction phase followed by intensive alternating cycles of non-cross-resistant chemotherapy and prolonged oral maintenance therapy. Eighty-one consecutive previously untreated patients were entered on this study. Ninety-four percent of patients entered complete remission. A Kaplan-Meier analysis predicts that 53% +/- 9% (SEM) of patients in remission will remain free of disease at 3 years. Neither age, sex, WBC count, nor immunophenotype had a significant effect on remission duration. This program of intensive cyclical chemotherapy has improved the disease-free survival of patients with adult ALL.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0006-4971
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1242-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3470055-Adolescent,
pubmed-meshheading:3470055-Adult,
pubmed-meshheading:3470055-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:3470055-Female,
pubmed-meshheading:3470055-Humans,
pubmed-meshheading:3470055-Leukemia, Lymphoid,
pubmed-meshheading:3470055-Male,
pubmed-meshheading:3470055-Middle Aged,
pubmed-meshheading:3470055-Prognosis
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pubmed:year |
1987
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pubmed:articleTitle |
Improved results of treatment of adult acute lymphoblastic leukemia.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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