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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1987-3-11
|
| pubmed:abstractText |
Calmodulin levels are elevated three- to fourfold in the dividing cells, resulting from the lectin-induced stimulation of fresh human lymphocytes. This increase in calmodulin appears to be related mainly to progression into S phase and supports the hypothesis that calmodulin might be crucial in regulating the progression of lymphoblasts through their division cycle. Calmodulin levels are higher in a lymphoid cell line derived from human acute lymphoblastic leukemia blood cells than in a lymphoid cell line derived from normal human blood cells, suggesting that calmodulin could be an important mediator of the leukemogenetic process.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0014-4827
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
168
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
546-54
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3467978-Calmodulin,
pubmed-meshheading:3467978-Cell Division,
pubmed-meshheading:3467978-Cell Line,
pubmed-meshheading:3467978-Cells, Cultured,
pubmed-meshheading:3467978-DNA Replication,
pubmed-meshheading:3467978-Flow Cytometry,
pubmed-meshheading:3467978-Humans,
pubmed-meshheading:3467978-Interphase,
pubmed-meshheading:3467978-Kinetics,
pubmed-meshheading:3467978-Leukemia, Lymphoid,
pubmed-meshheading:3467978-Lymphocyte Activation,
pubmed-meshheading:3467978-Lymphocytes
|
| pubmed:year |
1987
|
| pubmed:articleTitle |
Calmodulin in lymphocyte mitogenic stimulation and in lymphoid cell line growth.
|
| pubmed:publicationType |
Journal Article
|